منابع مشابه
Michael T. McManus: Interrupting biology
The human genome encodes snippets of RNAs ranging from 21–23 nucleotides in length, called microRNAs (miRNAs). Rather than code for proteins, miRNAs instead sabotage the translation of mRNAs. miRNAs are first generated as longer, hairpin-like precursors in the nucleus. In the cytoplasm, a collection of enzymes strips down the hairpins into their tiny and unwound final structure. miRNA-bound mRN...
متن کاملR waves interrupting T waves.
In the course of some experiments on anesthetized dogs and cats concerned with the production experimentally of ventricular flutter and ventricular fibrillation, Fastier and Smirk (1948) noted that R waves sometimes appeared on the descent of the antecedent T waves, shortly before the onset of veittricular flutter. The flutter was induced by a substance amarin * which had been found by one of u...
متن کاملMichael Rape: the biology of destruction
Michael Rape says that ubiquitination's diversity and adaptability makes it an ideal entry point for understanding vast swaths of biology.
متن کاملReply to Rychlik and McManus.
We read with interest the paper by Ikeda et al. [1] regarding the treatment of catamenial pneumothoraces. We agree with the authors that the pathology of true catamenial pneumothorax is not clear. However, in most cases, diaphragmatic fenestrations play a role. On the left, the fenestrations are frequently plugged by the omentum. On the right, however, the liver prevents such plugging, which ac...
متن کاملMichael Bevan: Setting up T cell selection
Every mature T cell specifically recognizes a particular combination of self-MHC molecule bound to a foreign peptide antigen. However, newborn T cells do not start out with the ability to recognize these complexes. During development, T cells re arrange their T cell receptor (TCR) genes, thus generating a diverse repertoire that includes those that do not recognize self-MHC. Only those that bin...
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ژورنال
عنوان ژورنال: Journal of Experimental Medicine
سال: 2008
ISSN: 1540-9538,0022-1007
DOI: 10.1084/jem.2053pi